BioForge Pro Max comprises of the following natural ingredients

• Coleus Forskohlii (20% forskolin, HPLC tested)
• Fadogia Agrestis PE (Chromadex certified)
• 7-methoxyflavone (Indofine Chemicals certified)
• Cholecalciferol (Vitamin D3)

Forskolin:

Scientific studies relating to bodybuilding supplements have suggested that along with supporting thyroid output and thermogenesis, forskolin may promote anabolic effects.* Those effects occur through elevation of 3,5 cyclic adenosine monophosphate (cAMP); a second messenger important in hormone signaling.

cAMP elevation is fundamental in generating an anabolic and thermogenic condition, and forskolin is a legal and safe compound suggested to trigger increases in cAMP levels.* One study (Litosch, 1982) demonstrated that forskolin raises cAMP levels in fat cells.

This is crucial because it suggests the ability of the substance to boost lipolysis.* One more added benefit of forskolin; it increases cAMP independently of adrenaline which may help provide increased energy without the need to use any type of traditional stimulant like caffeine pre-workout and without the undesirable effects of stimulants.*

Forskolin and Testosterone -- So how can cAMP increase anabolism?

cAMP is a crucial signal for steroidogenesis (testosterone production) in the Leydig cells of the testes, by increasing levels of steroidogenic acute regulatory protein (StAR). Enhanced StAR production is essential to achieve higher androgen levels, because it's a Leydig cells cholesterol transfer protein and provides the building blocks for testosterone synthesis.

StAR activation is necessary for the stimulation of steroidogenic enzymes responsible for transfer of cholesterol to testosterone. Therefore, high cAMP levels may translate into higher levels of luteinizing hormone (the hormone responsible for mediating endogenous testosterone production), and when cAMP levels are enhanced, it acts as an intermediate in the signaling cascade that ranges from luteinizing hormone (LH) binding to testosterone production. By quickening the process, it has been suggested that an increase in anabolism and protein synthesis may occur.*

Fadogia Agrestis:

Recent university studies suggest that Fadogia Agrestis has the ability to support increased testosterone levels when compared to that of a control group.*

Fadogia Agrestis is suggested to work through its ability to support an increase in the productiveness of the testis through increased testicular cholesterol - the building block and direct precursor of testosterone.*

Fadogia Agrestis is thought to naturally increase the sensitivity and production of the testis which may result in testosterone production cycles which are higher and naturally occurring.*

Partnering with Chromadex Labs, the leader in analytical reference testing, Biotivia and Omega Sports (the company which supplies this top quality extract) are the only U.S. companies to have developed a certification test for Fadogia Agrestis to ensure you are getting 100% pure Fadogia Agrestis.

Don't take chances with any other Fadogia product! Only Biotivia and Omega Sports have been certified--at the time of this writing pure--by the leading analytical lab in the country and is validated by an unprecedented level of very satisfied customer feedback.

7-methoxyflavone:

Aromatase enzymes are part of the body's biochemistry system that are used in the conversion of testosterone to estrogen. So, when aromatase enzyme activity is inhibited, this prevents conversion of testosterone into estrogen thus preventing the negative feedback loop in the HPTA (Hypothalamic-Pituitary-Testicular-Axis).

During the researchers constant effort for discovering a naturally occurring (7-methoxyflavone has been found in extracts from Meliaceae and Rutaceae plants) improved aromatase-inhibiting product, their attention was drawn to this compound. While several of these substances exhibited high aromatase-inhibiting activity, when it came to intestinal absorption and metabolic stability in the body, it was determined that there was a clear grouping of the majority of flavonoids that scored low (Chrysin anyone?) and only a few that scored high. When subjected to independent research, it was suggested that 7-methoxiflavone had one of the highest aromatase-inhibiting scores, with high intestinal absorption and metabolic stability in the body.*

These characteristics are extremely important for developing an effective, naturally occurring aromatase inhibitor. Even if a substance has high aromatase-inhibiting activity, if it is poorly absorbed or unstable metabolized quickly in the body, it will be ineffective. Therefore 7-methoxyflavone is our top choice due to its combination of characteristics required for maximum aromatase-inhibiting activity inside the body.*

Flavones are plant chemicals that have been suggested to be competitive inhibitors of cytochrome P450 aromatase with respect to the androgen substrate.*

A welcome plus with the 7-methoxyflavone is that it's not only orally available and resistant to metabolism but unlike most flavones it's very selective, it inhibits aromatase but not 17beta-hydroxysteroid dehydrogenase.

Optimal 17b-HSD activity is crucial for the endogenous testosterone synthesis. The 7-meth here shines again.

Biotivia is THE ONLY company at the time of this writing getting its 7-methoxyflavone from Indofine Chemicals, the company which supplied the ultra-pure flavone for many of the studies.

Cholecalciferol:

The bulk of this essential nutrient is made by the skin on exposure to sunlight. The rest comes from the diet.

A study in Clinical Endocrinology journal of 2,299 men, suggests that those with enough of the vitamin had more of the male sex hormone than those with less*, plus:

- Blood levels of both dipped in the winter and peaked in the summer.

- Low testosterone levels can zap energy levels.

- It also performs essential functions in both men and women such as maintaining muscle strength and bone density.*

The researchers from the Medical University of Graz, Austria, suggested that men with at least 30 nanograms of vitamin D per milliliter of blood had much more testosterone circulating than those lacking in vitamin D.*

Across the 2,299 men studied, testosterone and vitamin D levels appeared to peak in the month of August, and drop off in the winter, hitting their lowest levels in March.

Several animal studies also suggest a correlation between vitamin D3 status and LH/Testosterone levels.* Over the past decades the researchers have also suggested a positive role of Vitamin D3 on fat loss and increased muscle strength.*